Understanding how to use tretinoin will help you get the best results with fewer side effects. It's important to make sure you cover all your problem areas, but without using too much medication. Apply lightly over your skin's problem areas and rub in gently. Show
Tretinoin is effective but it can cause dryness, itchiness, redness, and other skin concerns. Using this medication as directed can help reduce your risk of these issues. This article walks you through how to use tretinoin and get the best results. It also explores exactly why tretinoin works and the possible side effects it can cause. Starting and Using Tretinoin, Step by StepVerywell / Brianna Gilmartin Tretinoin cream is commonly applied at night before bed. Follow these step-by-step instructions for how to use tretinoin cream:
When you first start using tretinoin, plan to apply it every other night or every third night. Skin flaking and irritation are usually the worst in the first two weeks, and this will allow your skin some time to adapt to the medicine. As it does, you can apply it more frequently, as directed. Some additional things to know:
Don't Give UpIf you notice an increase in irritation or flaking, it's OK to take a break from using tretinoin for a couple of days. Just don't stop using it completely without consulting your healthcare provider. Some people give up on tretinoin after a couple of days or weeks, assuming it didn't work. In actuality, their skin just needed time to adjust to the medication. What Tretinoin Does and How Soon It WorksAcne usually begins when a pore (a hair follicle) becomes clogged with dead skin, bacteria, and oil. This causes a bump called a comedone. Tretinoin works by increasing the production and shedding of skin cells (called cell turnover), which forces the plugged material out of the pore. It also prevents the formation of new comedones. It's important to realize that tretinoin works well on blackheads and whiteheads, but it may take six to nine weeks of use to see a noticeable difference in acne. This is a short wait compared to how long it takes to see a noticeable difference in wrinkles: at least six months. In fact, you'll get the greatest benefit from tretinoin if you use it for at least a year. Side Effects to Look Out ForSide effects of tretinoin can occur in anyone, but are particularly common in those with sensitive skin. Possible side effects include:
Diligent use of a quality moisturizer may help you avoid or minimize some of these. Tell your healthcare provider if you experience any of these side effects. You may need to stop using tretinoin. Is Tretinoin Safe for Everyone?Retin-A may negatively interact with other topical medications, especially those containing sulfur, resorcinol, or salicylic acid. To prevent dangerous interactions, make sure to tell your healthcare provider about all the medications—topical, oral, over-the-counter, and prescription—that you use. As tretinoin makes skin more sensitive to the sun, it may not be a good choice for those who are already sun-sensitive for other reasons. Little tretinoin is absorbed into the bloodstream when you use it topically, so breastfeeding when using the medication is generally
considered safe. Talk to your healthcare provider about how to use the medication if you're pregnant or thinking about becoming pregnant. They may advise you to hold off because too little is known about the effects of tretinoin on unborn babies. SummaryTretinoin cream is the go-to choice for treating acne and reducing the appearance of wrinkles. But this is one treatment that requires patience. To see results from acne, it takes about six to nine weeks. For wrinkles, it takes at least six months to a year. Initially, the medication can cause the skin to turn red and flake. Take it slow, follow all of the instructions on how to use tretinoin properly, and speak to your prescriber if you have persistent side effects. Frequently Asked Questions
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Heather L. Brannon, MD Thanks for your feedback! Should I apply moisturizer after tretinoin?To prevent skin dryness, people using tretinoin should use a moisturizer. Additionally, as it can make their skin photosensitive, it is advisable to apply tretinoin once a day, in the evening. Individuals who use tretinoin for acne will likely notice their acne worsening right after they begin treatment.
Should you let tretinoin dry before moisturizer?Wait 20 to 30 minutes before applying this medicine to make sure the skin is completely dry. Applying tretinoin to wet skin can irritate it. To use the cream, gel, or lotion form of this medicine: Apply just enough medicine to very lightly cover the affected areas, and rub in gently but well.
How long should I wait to apply moisturizer after tretinoin?A pea-sized amount will cover your full face. Step 3: Gently rub it into the treatment area. Step 4: Wash the medicine off your hands. Step 5: Wait 20 minutes, then apply moisturizer.
When should I apply tretinoin in my skincare routine?It should be used at bedtime, after cleansing with a gentle non-soap cleanser such as Cetaphil or CeraVe. It is more readily absorbed by wet skin, so either dry using a blow dryer on a cool setting or wait 20 minutes post-cleansing. After applying, follow by moisturizing cream.
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