What is the function of liver in digestive system

• Overview
• Anatomy
• Conditions and Disorders
• Care

Overview

What is the digestive system?

Your digestive system is made up of the gastrointestinal (GI) tract and your liver, pancreas and gallbladder. The GI tract is a series of hollow organs that are connected to each other from your mouth to your anus. The organs that make up your GI tract, in the order that they are connected, include your mouth, esophagus, stomach, small intestine, large intestine and anus.

What does the digestive system do?

Your digestive system is uniquely constructed to do its job of turning your food into the nutrients and energy you need to survive. And when it’s done with that, it handily packages your solid waste, or stool, for disposal when you have a bowel movement.

Why is digestion important?

Digestion is important because your body needs nutrients from the food you eat and the liquids you drink in order to stay healthy and function properly. Nutrients include carbohydrates, proteins, fats, vitamins, minerals and water. Your digestive system breaks down and absorbs nutrients from the food and liquids you consume to use for important things like energy, growth and repairing cells.

Anatomy

What organs make up the digestive system?

The main organs that make up the digestive system (in order of their function) are the mouth, esophagus, stomach, small intestine, large intestine, rectum and anus. Helping them along the way are the pancreas, gall bladder and liver.

Here’s how these organs work together in your digestive system.

Mouth

The mouth is the beginning of the digestive tract. In fact, digestion starts before you even take a bite. Your salivary glands get active as you see and smell that pasta dish or warm bread. After you start eating, you chew your food into pieces that are more easily digested. Your saliva mixes with the food to begin to break it down into a form your body can absorb and use. When you swallow, your tongue passes the food into your throat and into your esophagus.

Esophagus

Located in your throat near your trachea (windpipe), the esophagus receives food from your mouth when you swallow. The epiglottis is a small flap that folds over your windpipe as you swallow to prevent you from choking (when food goes into your windpipe). A series of muscular contractions within the esophagus called peristalsis delivers food to your stomach.

But first a ring-like muscle at the bottom of your esophagus called the lower esophageal sphincter has to relax to let the food in. The sphincter then contracts and prevents the contents of the stomach from flowing back into the esophagus. (When it doesn’t and these contents flow back into the esophagus, you may experience acid reflux or heartburn.)

Stomach

The stomach is a hollow organ, or "container," that holds food while it is being mixed with stomach enzymes. These enzymes continue the process of breaking down food into a usable form. Cells in the lining of your stomach secrete a strong acid and powerful enzymes that are responsible for the breakdown process. When the contents of the stomach are processed enough, they’re released into the small intestine.

Small intestine

Made up of three segments — the duodenum, jejunum, and ileum — the small intestine is a 22-foot long muscular tube that breaks down food using enzymes released by the pancreas and bile from the liver. Peristalsis also works in this organ, moving food through and mixing it with digestive juices from the pancreas and liver.

The duodenum is the first segment of the small intestine. It’s largely responsible for the continuous breaking-down process. The jejunum and ileum lower in the intestine are mainly responsible for the absorption of nutrients into the bloodstream.

Contents of the small intestine start out semi-solid and end in a liquid form after passing through the organ. Water, bile, enzymes and mucus contribute to the change in consistency. Once the nutrients have been absorbed and the leftover-food residue liquid has passed through the small intestine, it then moves on to the large intestine (colon).

Pancreas

The pancreas secretes digestive enzymes into the duodenum that break down protein, fats and carbohydrates. The pancreas also makes insulin, passing it directly into the bloodstream. Insulin is the chief hormone in your body for metabolizing sugar.

Liver

The liver has many functions, but its main job within the digestive system is to process the nutrients absorbed from the small intestine. Bile from the liver secreted into the small intestine also plays an important role in digesting fat and some vitamins.

The liver is your body's chemical "factory." It takes the raw materials absorbed by the intestine and makes all the various chemicals your body needs to function.

The liver also detoxifies potentially harmful chemicals. It breaks down and secretes many drugs that can be toxic to your body.

Gallbladder

The gallbladder stores and concentrates bile from the liver, and then releases it into the duodenum in the small intestine to help absorb and digest fats.

Colon

The colon is responsible for processing waste so that emptying your bowels is easy and convenient. It’s a 6-foot long muscular tube that connects the small intestine to the rectum.

The colon is made up of the cecum, the ascending (right) colon, the transverse (across) colon, the descending (left) colon, and the sigmoid colon, which connects to the rectum.

Stool, or waste left over from the digestive process, is passed through the colon by means of peristalsis, first in a liquid state and ultimately in a solid form. As stool passes through the colon, water is removed. Stool is stored in the sigmoid (S-shaped) colon until a "mass movement" empties it into the rectum once or twice a day.

It normally takes about 36 hours for stool to get through the colon. The stool itself is mostly food debris and bacteria. These “good” bacteria perform several useful functions, such as synthesizing various vitamins, processing waste products and food particles and protecting against harmful bacteria. When the descending colon becomes full of stool, or feces, it empties its contents into the rectum to begin the process of elimination (a bowel movement).

Rectum

The rectum is a straight, 8-inch chamber that connects the colon to the anus. The rectum's job is to receive stool from the colon, let you know that there is stool to be evacuated (pooped out) and to hold the stool until evacuation happens. When anything (gas or stool) comes into the rectum, sensors send a message to the brain. The brain then decides if the rectal contents can be released or not.

If they can, the sphincters relax and the rectum contracts, disposing its contents. If the contents cannot be disposed, the sphincter contracts and the rectum accommodates so that the sensation temporarily goes away.

Anus

The anus is the last part of the digestive tract. It is a 2-inch long canal consisting of the pelvic floor muscles and the two anal sphincters (internal and external). The lining of the upper anus is able to detect rectal contents. It lets you know whether the contents are liquid, gas or solid.

The anus is surrounded by sphincter muscles that are important in allowing control of stool. The pelvic floor muscle creates an angle between the rectum and the anus that stops stool from coming out when it’s not supposed to. The internal sphincter is always tight, except when stool enters the rectum. This keeps us continent (prevents us from pooping involuntarily) when we are asleep or otherwise unaware of the presence of stool.

When we get an urge to go to the bathroom, we rely on our external sphincter to hold the stool until reaching a toilet, where it then relaxes to release the contents.

Conditions and Disorders

What are some common conditions that affect the digestive system?

There are temporary conditions and long-term, or chronic, diseases and disorders that affect the digestive system. It’s common to have conditions such as constipation, diarrhea or heartburn from time to time. If you are experiencing digestive issues like these frequently, be sure to contact your healthcare professional. It could be a sign of a more serious disorder that needs medical attention and treatment.

Short-term or temporary conditions that affect the digestive system include:

• Constipation: Constipation generally happens when you go poop (have a bowel movement) less frequently than you normally do. When you’re constipated, your poop is often dry and hard and it’s difficult and painful for your poop to pass.
• Diarrhea: Diarrhea is when you have loose or watery poop. Diarrhea can be caused by many things, including bacteria, but sometimes the cause is unknown.
• Heartburn: Although it has “heart” in its name, heartburn is actually a digestive issue. Heartburn is an uncomfortable burning feeling in your chest that can move up your neck and throat. It happens when acidic digestive juices from your stomach go back up your esophagus.
• Hemorrhoids: Hemorrhoids are swollen, enlarged veins that form inside and outside of your anus and rectum. They can be painful, uncomfortable and cause rectal bleeding.
• Stomach flu (gastroenteritis): The stomach flu is an infection of the stomach and upper part of the small intestine usually caused by a virus. It usually lasts less than a week. Millions of people get the stomach flu every year.
• Ulcers: An ulcer is a sore that develops on the lining of the esophagus, stomach or small intestine. The most common causes of ulcers are infection with a bacteria called Helicobacter pylori (H. pylori) and long-term use of anti-inflammatory drugs such as ibuprofen.
• Gallstones: Gallstones are small pieces of solid material formed from digestive fluid that form in your gallbladder, a small organ under your liver.

Common digestive system diseases (gastrointestinal diseases) and disorders include:

• GERD (chronic acid reflux): GERD (gastroesophageal reflux disease, or chronic acid reflux) is a condition in which acid-containing contents in your stomach frequently leak back up into your esophagus.
• Irritable bowel syndrome (IBS): IBS is a condition in which your colon muscle contracts more or less often than normal. People with IBS experience excessive gas, abdominal pain and cramps.
• Lactose intolerance: People with lactose intolerance are unable to digest lactose, the sugar primarily found in milk and dairy products.
• Diverticulosis and diverticulitis: Diverticulosis and diverticulitis are two conditions that occur in your large intestine (also called your colon). Both share the common feature of diverticula, which are pockets or bulges that form in the wall of your colon.
• Cancer: Cancers that affect tissues and organs in the digestive system are called gastrointestinal (GI) cancers. There are multiple kinds of GI cancers. The most common digestive system cancers include esophageal cancer, gastric (stomach) cancer, colon and rectal (colorectal) cancer, pancreatic cancer and liver cancer.
• Crohn’s disease: Crohn’s disease is a lifelong form of inflammatory bowel disease (IBD). The condition irritates the digestive tract.
• Celiac disease: Celiac disease is an autoimmune disorder that can damage your small intestine. The damage happens when a person with celiac disease consumes gluten, a protein found in wheat, barley and rye.

Care

How can I keep my digestive system healthy?

If you have a medical condition, always ask your healthcare provider what you should do and eat to stay healthy and manage your condition. In general, the following are ways to keep your digestive system healthy:

• Drink water often: Water helps the food you eat flow more easily through your digestive system. Low amounts of water in your body (dehydration) is a common cause of constipation.
• Include fiber in your diet: Fiber is beneficial to digestion and helps your body have regular bowel movements. Be sure to incorporate both soluble and insoluble fiber into your diet.
• Eat a balanced diet: Be sure to eat several servings of fruit and vegetables every day. Choose whole grains over processed grains and try to avoid processed foods in general. Choose poultry and fish more often than red meat and limit all deli (processed) meats. Limit the amount of sugar you consume.
• Eat foods with probiotics or take probiotic supplements: Probiotics are good bacteria that help fight off the bad bacteria in your gut. They also make healthy substances that nourish your gut. It can be especially helpful to consume probiotics after you have taken an antibiotic because antibiotics often kill both bad and good bacteria in your gut.
• Eat mindfully and chew your food: Eating slowly gives your body time to digest your food properly. It also allows your body to send you cues that it is full. It is important to chew your food thoroughly because it helps to ensure your body has enough saliva (spit) for digestion. Chewing your food fully also makes it easier for your digestive system to absorb the nutrients in the food.
• Exercise: Physical activity and gravity help move food through your digestive system. Taking a walk, for example, after you eat a meal can help your body digest the food more easily.
• Avoid alcohol and smoking: Alcohol can increase the amount of acid in your stomach and can cause heartburn, acid reflux and stomach ulcers. Smoking almost doubles your risk of having acid reflux. Research has shown that people who have digestive issues that quit smoking have improved symptoms.
• Manage your stress: Stress is associated with digestive issues such as constipation, diarrhea and IBS.

When should I contact my healthcare provider about digestive system issues?

Contact your healthcare provider if you are experiencing frequent symptoms such as constipation, diarrhea, vomiting, stomach pain or cramps, excessive gas (farting), or heartburn. While most people experience these conditions every once in a while, if you experience them often, it could be a sign of a more serious digestive system issue.

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Last reviewed by a Cleveland Clinic medical professional on 08/09/2021.

References

• National Institute of Diabetes and Digestive and Kidney Diseases. Your digestive system & how it works. (https://www.niddk.nih.gov/health-information/digestive-diseases/digestive-system-how-it-works) Accessed 6/10/2021.
• Merck Manual Home Health Handbook. Overview of the Digestive System. (http://www.merckmanuals.com/home/digestive_disorders/biology_of_the_digestive_system/overview_of_the_digestive_system.html?qt=digestive&alt=sh) Accessed 6/10/2021.
• National Cancer Institute SEER Training Modules. Introduction to the Digestive System. (https://training.seer.cancer.gov/anatomy/digestive/) Accessed 6/10/2021.

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