Whats the difference between vitamin d2 and vitamin d3

The Difference Between Vitamin D, D2, and D3

Vitamin D is an essential nutrient required for the body to perform many functions including assisting its ability to absorb other minerals.

Vitamin D is an important component in maintaining general health and wellbeing. It helps to keep bones, teeth, and muscles strong. It also supports healthy immune function and plays a pivotal role in balancing the nervous system.  Studies have indicated that vitamin D may be beneficial in improving mood and mental health conditions such as depression and anxiety. 

Where do we get Vitamin D?

The main source of vitamin D is sunshine. It is produced by the body through sunlight on the skin. However, many people, especially those living in colder climates, are deficient and may require additional supplementation.

Through the winter months in the UK, many of us don’t get adequate levels through sunlight exposure so supplementation may be required.

Vitamin D can also be obtained through diet, eating foods that have a high Vitamin D content such as:

  •   Oily fish – trout, salmon, sardines, herring, and mackerel
  •   Egg yolks
  •   Mushrooms
  •   Fortified foods – breakfast cereals, margarine, orange juice
  •   Red meat
  •   Liver

What is the difference between Vitamin D, D2, and D3?

There are two main types of vitamin D – vitamin D2 (ergocalciferol) and D3 (cholecalciferol), which have slightly different molecular structures but work to perform the same roles in the body.

Vitamin D2 is derived from plants whereas D3 comes from animals and sunshine.

Which one is better – Vitamin D2 or Vitamin D3?

Vitamin D is measured in the body by the levels of calcifediol (the two compounds that are made by vitamin D2 and D3 when they are metabolised).

Both vitamin D2 and D3 are absorbed effectively into the bloodstream, however, they are metabolised differently by the liver.

It is thought the D3 is more stable and nearly twice as effective at raising blood levels of calcifediol in the blood than D2.

What are the sources of Vitamin D3?

Foods that are naturally high in vitamin D3 are derived from animal sources such as cod liver oil, trout, and salmon. Smaller amounts of D3 can be found in eggs, sardines, tuna, and beef liver.

Whats the difference between vitamin d2 and vitamin d3

Vitamin D3 is also produced when the skin is exposed to sunlight, specifically ultraviolet B (UVB). Unlike vitamin D supplementation, you cannot overdose on Vitamin D3 produced by sunlight – when the body has enough it simply produces less. It’s important to remember adequate sun protection, though!

What are the sources of Vitamin D2?

Very few foods are high in vitamin D2 but there are some which are fortified to increase the levels including cereals, orange juice, cow’s milk, and plant milk (like almond, oat, and soya milk). It’s important to check the labels for vitamin D fortification as this varies from country to country and within brands.

Produce that has high exposure to sunlight such as mushrooms are naturally high in vitamin D2. 

What is Vitamin D3 good for?

Vitamin D3 serves a vital role in the body, helping it absorb calcium and phosphorus which are important for building bones and keeping them strong and healthy. Vitamin D is often used as a preventative supplement for osteoporosis, osteopenia, and osteomalacia which are all diseases characterised by weakening or softening of the bones.

 What is the best time to take Vitamin D?

The best time to take Vitamin D is after consuming foods with a highfat content such as fullfat yoghurt or milk. This is because Vitamin D is a fat-soluble vitamin and absorbs best with fatty foods.

Just a small amount of fat is enough to be effective. If you’ve been prescribed vitamin D by your doctor, it’s important to follow the directions to get the best benefit.

Vitamin D supplementation

For people deficient in vitamin D who need to raise levels quickly, an intramuscular injection may be necessary.

IV Boost offers Vitamin D Shots in our convenient central London clinic via a prescription. All our treatments are overseen by a GMC-registered practitioner.

The process involves:

  1. Blood test – a reading of the Vitamin D levels in the blood is carried out to confirm a deficiency
  2. Consultation – a GMCregistered doctor will review medical history and suitability for the treatment
  3. Injection- if the patient is a suitable candidate for the vitamin D injection, this will be carried out
  4. Recovery – many people start feeling the effects immediately while others feel the benefits within 24 hours posttreatment.

Is it better to take vitamin D2 or D3?

Studies have repeatedly shown that vitamin D3 is superior at raising levels of vitamin D in the body. These findings were supported by a recent review of the evidence which found that vitamin D3 supplementation increased vitamin D levels in the body better than vitamin D2.

Why do doctors prescribe vitamin D2 instead of D3?

Vitamin D supplements are available as vitamin D2 (D2) and vitamin D3 (D3). Both versions can be used to treat vitamin D deficiency, but D3 seems to be more effective than D2. Vitamin D2 is still prescribed to people with low vitamin D levels, because it's more readily available in higher doses.

Do you need both vitamin D2 and D3?

Although you can safely take both vitamin D2 and D3 supplements, the effectiveness of the two forms of the vitamin differs. Experts agree that vitamin D3 is a preferable choice over D2. Not only is D3 the form that occurs naturally in the human body but it also raises blood levels of vitamin D much more effectively.

Is vitamin D2 equivalent to vitamin D3?

Vitamin D2 has been found to be either equivalent (12–14) or slightly less potent (15–18) than vitamin D3 for obtaining optimal serum 25OHD concentrations at least when given in daily dosages. However, when given intermittently vitamin D2 is clearly less potent than vitamin D3 (14, 19).